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β-Carotene

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By Targets:	Apoptosis (4) Bacterial (2) Bcl-2 Family (1) Biochemical Assay Reagents (1) Caspase (1) Cholinesterase (ChE) (2) COX (1) Endogenous Metabolite (5) IAP (1) Isotope-Labeled Compounds (2) Nucleoside Antimetabolite/Analog (1) Organoid (1) Reactive Oxygen Species (ROS) (3) Reference Standards (1) TNF Receptor (1)
By Research Areas:	Cancer (6) Infection (2) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (2)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0411

*β-Carotene* 2 Publications Verification Provitamin A; beta-Carotene	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411S4

β-Carotene-13C10 Provitamin A-_{13_{C_{10_{; beta-Carotene-_{13_C₁₀}}}}}	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411S1

β-Carotene-d8 Provitamin A-d₈; beta-Carotene-d₈	Isotope-Labeled Compounds	Others
β-Carotene-d₈ is the deuterium labeled β-Carotene (HY-N0411) .

HY-W009310

9-cis-Retinal	Endogenous Metabolite Organoid	Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with K_ds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .

HY-N0411R

β-Carotene (Standard)	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N15378

β-Carotene-15,15'-epoxide	IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis	Inflammation/Immunology Cancer
β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .

HY-136234

9-cis-β-Carotene	Endogenous Metabolite	Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus .

HY-133183

Urolignoside	Biochemical Assay Reagents	Others
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-131803

3'-Azido-3'-deoxyguanosine	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W041301R

(±)-Dihydroactinidiolide (Standard)	Reference Standards Cholinesterase (ChE) Bacterial	Infection Neurological Disease Cancer
(±)-Dihydroactinidiolide (Standard) is the analytical standard of (±)-Dihydroactinidiolide (HY-W041301). This product is intended for research and analytical applications. (±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC₅₀ = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .

HY-W041301

(±)-Dihydroactinidiolide	Cholinesterase (ChE) Bacterial	Infection Neurological Disease Cancer
(±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC₅₀ = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0411

*β-Carotene* 2 Publications Verification Provitamin A; beta-Carotene	Structural Classification Classification of Application Fields Source classification Endocrine diseases Metabolic Disease Plants Endogenous metabolite Food Research Other Terpenoids Immune System Disorder other families Terpenoids Disease markers Pigments Disease Research Fields Cancer	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-W009310

9-cis-Retinal	Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite Organoid
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with K_ds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .

HY-W041301

(±)-Dihydroactinidiolide	Structural Classification Natural Products Nicotiana tabacum L. Classification of Application Fields Source classification Other Diseases Solanaceae Plants Disease Research Fields	Cholinesterase (ChE) Bacterial
(±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC₅₀ = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .

HY-N0411R

β-Carotene (Standard)	Other Terpenoids Structural Classification Immune System Disorder other families Terpenoids Source classification Disease markers Endocrine diseases Plants Endogenous metabolite Cancer	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N15378

β-Carotene-15,15'-epoxide	Structural Classification Natural Products Source classification Spondias mombin L. Plants Anacardiaceae	IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis
β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .

HY-133183

Urolignoside	Structural Classification Natural Products Source classification Cinnamomum verum J. Presl Plants Lauraceae	Biochemical Assay Reagents
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-W041301R

(±)-Dihydroactinidiolide (Standard)	Structural Classification Natural Products Nicotiana tabacum L. Source classification Solanaceae Plants	Reference Standards Cholinesterase (ChE) Bacterial
(±)-Dihydroactinidiolide (Standard) is the analytical standard of (±)-Dihydroactinidiolide (HY-W041301). This product is intended for research and analytical applications. (±)-Dihydroactinidiolide is the exo-isomer of Dihydroactinidiolide (HY-107805). Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect. Dihydroactinidiolide is also an inhibitor of AChE (IC₅₀ = 34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis .

Cat. No.	Product Name	Chemical Structure

HY-N0411S4

β-Carotene-13C10
β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

β-Carotene-13C10

β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411S1

β-Carotene-d8
β-Carotene-d₈ is the deuterium labeled β-Carotene (HY-N0411) .

Cat. No.	Product Name		Classification

HY-131803

3'-Azido-3'-deoxyguanosine		Azide
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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β-Carotene

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products