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  • HY-P74484
    UBASH3B/STS1 Protein, Human (His)

    Ubiquitin-associated and SH3 domain-containing protein B; Sts-1; TULA-2; UBASH3B

    		 Human E. coli
    UBASH3B/STS1 protein blocks CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases, leading to the accumulation of activating receptors such as T cell receptors and EGFR on the cell surface. It exhibits tyrosine phosphatase activity against substrates such as EGFR, FAK, SYK and ZAP70. UBASH3B/STS1 Protein, Human (His) is the recombinant human-derived UBASH3B/STS1 protein, expressed by E. coli , with N-His labeled tag.
  • HY-P76687
    UBASH3A Protein, Human (His)
    1 Publications Verification

    Ubiquitin-associated and SH3 domain-containing protein A; CLIP4; Sts-2; TULA-1

    		 Human E. coli
    UBASH3A interferes with CBL-mediated downregulation and degradation of receptor-type tyrosine kinases and promotes the accumulation of activating receptors such as T cell receptors, EGFR and PDGFRB on the cell surface. It exhibits minimal protein tyrosine phosphatase activity and may act as a dominant negative regulator of UBASH3B-dependent dephosphorylation. UBASH3A Protein, Human (His) is the recombinant human-derived UBASH3A protein, expressed by E. coli , with N-His labeled tag.

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