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Herc2

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  • HY-P701527
    HERC2 Protein, Human (His)

    Herc2; E3 ubiquitin-protein ligase Herc2; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase Herc2

    		 Human E. coli
    The HERC2 protein is an E3 ubiquitin protein ligase that tightly regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes, especially in response to ionizing radiation (IR). HERC2 is recruited to DNA damage sites and promotes the assembly of UBE2N and RNF8, promoting "Lys-63" linked ubiquitin chains to produce DNA damage-induced responses. HERC2 Protein, Human (His) is the recombinant human-derived HERC2 protein, expressed by E. coli , with N-6*His labeled tag.

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