2. GPCR/G Protein
  3. Adenosine Receptor
  4. SCH442416 (Standard)

SCH442416 (Standard) is the analytical standard of SCH442416. This product is intended for research and analytical applications. SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain.

For research use only. We do not sell to patients.

SCH442416 (Standard) Chemical Structure

SCH442416 (Standard) Chemical Structure

CAS No. : 316173-57-6

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SCH442416 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH442416 (Standard)316173-57-6Adenosine ReceptorP1 receptoradenosineA2AimagingInhibitorinhibitorinhibit

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