2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Sarcophine

Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum.

For research use only. We do not sell to patients.

Sarcophine

Sarcophine Chemical Structure

CAS No. : 55038-27-2

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Sarcophine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 5
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
[PMID: 21458279]
A549 ED50
10.38 μg/mL
Compound: 6
Cytotoxicity against human A549 cells after 6 days by MTT assay
Cytotoxicity against human A549 cells after 6 days by MTT assay
10.1021/np960174n
HCT-116 IC50
> 40 μM
Compound: 5
Cytotoxicity against human HCT116 cells by MTT assay
Cytotoxicity against human HCT116 cells by MTT assay
[PMID: 21458279]
HL-60 IC50
34.7 μM
Compound: 5
Cytotoxicity against human HL60 cells by MTT assay
Cytotoxicity against human HL60 cells by MTT assay
[PMID: 21458279]
HT-29 ED50
10.46 μg/mL
Compound: 6
Cytotoxicity against human HT29 cells after 6 days by MTT assay
Cytotoxicity against human HT29 cells after 6 days by MTT assay
10.1021/np960174n
KB ED50
> 50 μg/mL
Compound: 6
Cytotoxicity against human KB cells after 3 days by MTT assay
Cytotoxicity against human KB cells after 3 days by MTT assay
10.1021/np960174n
MCF7 IC50
> 40 μM
Compound: 5
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
[PMID: 21458279]
P388 ED50
2.42 μg/mL
Compound: 6
Cytotoxicity against mouse P388 cells after 3 days by MTT assay
Cytotoxicity against mouse P388 cells after 3 days by MTT assay
10.1021/np960174n
In Vitro

Sarcophine ((+)-Sarcophine) is an inhibitor of recombinant glycine receptors, with a Ki value of 2.1 μM[1].
Sarcophine (1-100 mM; 24 h) has cytotoxicity against HEK293 cells with an LD50 value of 29.3 mM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sarcophine Related Antibodies
Molecular Weight

316.43

Formula

C20H28O3
CAS No.
SMILES

O=C1C(C)=C2[C@](O1)([H])/C=C(C)/CC[C@H]3[C@](O3)(C)CC/C=C(C)/CC2
Structure Classification
Initial Source

Sarcophyton glaucum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Sarcophine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarcophine55038-27-2(+)-SarcophineEndogenous Metabolitenature productRed Sea soft coralSarcophyton glaucumglycineInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sarcophine
Cat. No.:
HY-124550
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.