1. Apoptosis
  2. c-Myc
  3. sAJM589

sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM.

For research use only. We do not sell to patients.

sAJM589 Chemical Structure

sAJM589 Chemical Structure

CAS No. : 2089-82-9

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Solution
10 mM * 1 mL in DMSO In-stock
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Based on 1 publication(s) in Google Scholar

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Description

sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].

IC50 & Target

IC50: 1.8 μM (Myc)[1]

In Vitro

sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC50 of 1.8 μM[1].
? sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

246.26

Formula

C16H10N2O

CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

OC1=CC2=NC3=CC=CC=C3N=C2C4=CC=CC=C41

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
sAJM589
Cat. No.:
HY-122683
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