2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Autophagy Anti-infection
  3. HMG-CoA Reductase (HMGCR) Potassium Channel Autophagy Bacterial
  4. Rosuvastatin Sodium (Standard)

Rosuvastatin Sodium (Standard) 

Cat. No.: HY-17504BR Purity: ≥98%
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Rosuvastatin (Sodium) (Standard) is the analytical standard of Rosuvastatin (Sodium). This product is intended for research and analytical applications. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

For research use only. We do not sell to patients.

Rosuvastatin Sodium (Standard) Chemical Structure

Rosuvastatin Sodium (Standard) Chemical Structure

CAS No. : 147098-18-8

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Description

Rosuvastatin (Sodium) (Standard) is the analytical standard of Rosuvastatin (Sodium). This product is intended for research and analytical applications. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

Molecular Weight

503.52

Formula

C22H27FN3NaO6S
CAS No.
SMILES

O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Rosuvastatin Sodium (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rosuvastatin Sodium (Standard)147098-18-8HMG-CoA Reductase (HMGCR)Potassium ChannelAutophagyBacterialKcsAhERGcardiacrepolarizationactionpotentialdurationsAPDsQTQTcHsp70low-densitylipoproteincholesteroltriglyceridesInhibitorinhibitorinhibit

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