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  4. Ro 31-6840

Ro 31-6840 is an active compound.

For research use only. We do not sell to patients.

Ro 31-6840

Ro 31-6840 Chemical Structure

CAS No. : 119555-47-4

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Ro 31-6840 Related Antibodies

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Description

Ro 31-6840 is an active compound.

Cellular Effect
Cell Line Type Value Description References
C8166 IC50
0.7 μM
Compound: 12
Antiviral activity against HIV-1 (RF strain) in C8166 cells
Antiviral activity against HIV-1 (RF strain) in C8166 cells
[PMID: 2165161]
CCRF-CEM EC50
1.1 μM
Compound: 10a
Effect on HIV-induced cytopathogenesis in CEM cells.
Effect on HIV-induced cytopathogenesis in CEM cells.
[PMID: 1351945]
CCRF-CEM IC50
43 μM
Compound: 10a
Effect on HIV-induced cytopathogenesis in CEM cells.
Effect on HIV-induced cytopathogenesis in CEM cells.
[PMID: 1351945]
CCRF-CEM IC50
> 100 μM
Compound: 13
Cytotoxicity in CEM cells
Cytotoxicity in CEM cells
10.1016/0960-894X(95)00133-E
HL-60 IC50
707 μM
Compound: 12
Cytotoxicity was tested in HL60 cells by the trypan blue exclusion assay.
Cytotoxicity was tested in HL60 cells by the trypan blue exclusion assay.
[PMID: 1695683]
HepG2 2.2.15 EC50
4 μM
Compound: 13
In vitro anti-HBV activity in 2.2.15 cells
In vitro anti-HBV activity in 2.2.15 cells
10.1016/0960-894X(95)00133-E
HepG2 2.2.15 IC50
> 200 μM
Compound: 13
Cytotoxicity in 2.2.15 cells
Cytotoxicity in 2.2.15 cells
10.1016/0960-894X(95)00133-E
MT4 EC50
2.54 μM
Compound: 12
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the reverse transcriptase (RT) assay
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the reverse transcriptase (RT) assay
[PMID: 1695683]
MT4 EC50
2.66 μM
Compound: 12
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the P24 antigen enzyme-linked immunosorbent assay (ELISA).
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the P24 antigen enzyme-linked immunosorbent assay (ELISA).
[PMID: 1695683]
MT4 ED50
9.8 μM
Compound: 14b
Inhibitory activity against HIV-1 replication in MT-4 cells
Inhibitory activity against HIV-1 replication in MT-4 cells
[PMID: 2754700]
MT4 IC50
872 μM
Compound: 12
Cytotoxicity was tested in MT-4 cells by the XTT-microculture tetrazolium assay.
Cytotoxicity was tested in MT-4 cells by the XTT-microculture tetrazolium assay.
[PMID: 1695683]
Vero IC50
> 100 μM
Compound: 13
Cytotoxicity in Vero cells
Cytotoxicity in Vero cells
10.1016/0960-894X(95)00133-E
Molecular Weight

229.21

Formula

C9H12FN3O3
CAS No.
SMILES

OC[C@@H]1C[C@H](F)[C@H](N2C=CC(N)=NC2=O)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ro 31-6840 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ro 31-6840119555-47-42'βFddCDrug DerivativeDrug derivativeInhibitorinhibitorinhibit

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