VEGF-B Protein, Human (HEK293,His)

VEGF-BB protein is an endothelial cell-specific growth factor with VEGF-B167 and VEGF-B186 isoforms and has a unique binding ability to heparin and Neuropilin-1. VEGF-B Protein, Human (HEK293,His) is the recombinant human-derived VEGF-B protein, expressed by HEK293, with C-His labeled tag.

VEGF-B, or vascular endothelial growth factor B, is a protein that plays a role in cell survival and possibly in cardiac and metabolic function. VEGF-B, unlike VEGF-A, acts primarily as an angiogenic (blood vessel growth) factor and does not strongly induce blood vessel growth in most tissues. However, VEGF-B can promote coronary blood vessel growth and protect the heart from ischemic injury. VEGF-B also has survival effects on a variety of cell types, including neurons and cardiomyocytes, by inhibiting apoptosis (programmed cell death).

Human

HEK293

C-His

P49765-1 (P22-A207)

7423

Full Length of Isoform-1 Mature Protein

Approximately 16 kDa & 34-40 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.