2. Recombinant Proteins
  3. Enzymes & Regulators
  4. STAT5A Protein, Human (sf9, His)

STAT5A Protein, Human (sf9, His) is the recombinant human-derived STAT5, expressed by Sf9 insect cells , with His labeled tag. ,

For research use only. We do not sell to patients.

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Description

STAT5A Protein, Human (sf9, His) is the recombinant human-derived STAT5, expressed by Sf9 insect cells , with His labeled tag. ,
Background

STAT5 performs a dual function: signal transduction and activation of transcription. It mediates cellular responses to the cytokine KITLG/SCF and other growth factors, as well as responses to ERBB4. STAT5 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3, and FGFR4. It binds to the GAS element and activates PRL-induced transcription. During lactation, STAT5 regulates the expression of milk proteins. by similar: STAT5 is also involved in mediating cellular responses to other growth factors and may play roles in multiple signaling pathways.
Species

Human
Source

Sf9 insect cells
Tag

His
Accession

P42229-1 (M1-S794)
Gene ID

6776
Protein Length

Full Length of Isoform-1
Synonyms
STAT5
Predicted Molecular Mass
92 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Documentation
Handling Instructions (2659 KB)

STAT5A Protein, Human (sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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