2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. TNF Superfamily
  5. TNF Receptor Superfamily
  6. Decoy Receptor 1
  7. TNFRSF10C Protein, Human (213a.a, HEK293, His)

TNFRSF10C Protein, Human (213a.a, HEK293, His)

Cat. No.: HY-P703850
Handling Instructions Technical Support

TNFRSF10C Protein, Human (213a.a, HEK293, His) is the recombinant human-derived TNFRSF10C protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

TNFRSF10C Protein, Human (213a.a, HEK293, His) is the recombinant human-derived TNFRSF10C protein, expressed by HEK293, with C-His tag.
Background

The TNFRSF10C Protein serves as a receptor for the cytotoxic ligand TRAIL; however, it lacks a cytoplasmic death domain, rendering it incapable of inducing apoptosis. Instead, TNFRSF10C may play a protective role in cells by competing with TRAIL-R1 and R2 for binding to the ligand, potentially acting as a decoy receptor and thereby mitigating TRAIL-mediated apoptosis. This unique feature highlights the regulatory complexity of TNFRSF10C in modulating cellular responses to TRAIL signaling and suggests its involvement in fine-tuning the balance between survival and apoptotic pathways.
Species

Human
Source

HEK293
Tag

C-8*His
Accession

Q05D71 (Y24-A236)
Gene ID

/
Protein Length

Partial
Synonyms
DcR1; TRAILR3
Predicted Molecular Mass
23.5 kDa
Molecular Weight

Approximately 60-80 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

TNFRSF10C Protein, Human (213a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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