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  4. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi)

B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi)

Cat. No.: HY-P703878
Handling Instructions Technical Support

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293, with C-His and C-Avi labeled tag.

For research use only. We do not sell to patients.

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Description

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293, with C-His and C-Avi labeled tag.
Background

B7-2/CD86 protein functions as a negative regulator of T-cell activation by disrupting the formation of CD86 clusters. Through this interference, it modulates the T-cell response and plays a role in regulating immune activation.
Species

Human
Source

HEK293
Tag

C-His;Avi
Accession

P42081-3 (K21-H239)
Gene ID

942
Protein Length

Partial
Synonyms
CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2
Predicted Molecular Mass
28.4 kDa
Molecular Weight

Approximately 44.64-67.56 kDa,based on SDS-PAGE under reducing conditions.
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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