1. Anti-infection
  2. Bacterial
  3. (R,R)-BAY-Y 3118

(R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity.

For research use only. We do not sell to patients.

(R,R)-BAY-Y 3118 Chemical Structure

(R,R)-BAY-Y 3118 Chemical Structure

CAS No. : 151213-22-8

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Based on 1 publication(s) in Google Scholar

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Description

(R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity[1].

In Vitro

(R,R)-BAY-Y 3118 shows bactericidal activity ranges from a log 1/C 5.65-7.47 for Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

405.85

Formula

C20H21ClFN3O3

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

ClC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4C[C@]5([H])[C@](NCCC5)([H])C4)=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (308.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4640 mL 12.3198 mL 24.6396 mL
5 mM 0.4928 mL 2.4640 mL 4.9279 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4640 mL 12.3198 mL 24.6396 mL 61.5991 mL
5 mM 0.4928 mL 2.4640 mL 4.9279 mL 12.3198 mL
10 mM 0.2464 mL 1.2320 mL 2.4640 mL 6.1599 mL
15 mM 0.1643 mL 0.8213 mL 1.6426 mL 4.1066 mL
20 mM 0.1232 mL 0.6160 mL 1.2320 mL 3.0800 mL
25 mM 0.0986 mL 0.4928 mL 0.9856 mL 2.4640 mL
30 mM 0.0821 mL 0.4107 mL 0.8213 mL 2.0533 mL
40 mM 0.0616 mL 0.3080 mL 0.6160 mL 1.5400 mL
50 mM 0.0493 mL 0.2464 mL 0.4928 mL 1.2320 mL
60 mM 0.0411 mL 0.2053 mL 0.4107 mL 1.0267 mL
80 mM 0.0308 mL 0.1540 mL 0.3080 mL 0.7700 mL
100 mM 0.0246 mL 0.1232 mL 0.2464 mL 0.6160 mL
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(R,R)-BAY-Y 3118 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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