2. Autophagy
  3. p62
  4. PTX80

PTX80 is an antagonist of p62 with an IC50 value of 31.18 nM. PTX80 reduces tumor volume in an HCT116 colorectal cancer mouse xenograft model.

For research use only. We do not sell to patients.

PTX80 Chemical Structure

PTX80 Chemical Structure

CAS No. : 2376297-69-5

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PTX80 Related Antibodies

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Description

PTX80 is an antagonist of p62 with an IC50 value of 31.18 nM. PTX80 reduces tumor volume in an HCT116 colorectal cancer mouse xenograft model[1].

Molecular Weight

474.57

Formula

C26H26N4O3S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(/C(CN(C/1)S(CCCN(C)C)(=O)=O)=C/C2=CC=C(C=C2)C#N)C1=C\C3=CC=C(C=C3)C#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.3%

SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References
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PTX80 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PTX802376297-69-5PTX 80PTX-80p62Sequestosome-1SQSTM1HCT116Inhibitorinhibitorinhibit

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