1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Prostaglandin F2α serinol amide

Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord.

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Prostaglandin F2α serinol amide Chemical Structure

Prostaglandin F2α serinol amide Chemical Structure

CAS No. : 1135226-99-1

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Description

Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord[1][2][3].

Molecular Weight

427.57

Formula

C23H41NO6

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

OCC(CO)NC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (233.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3388 mL 11.6940 mL 23.3880 mL
5 mM 0.4678 mL 2.3388 mL 4.6776 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3388 mL 11.6940 mL 23.3880 mL 58.4700 mL
5 mM 0.4678 mL 2.3388 mL 4.6776 mL 11.6940 mL
10 mM 0.2339 mL 1.1694 mL 2.3388 mL 5.8470 mL
15 mM 0.1559 mL 0.7796 mL 1.5592 mL 3.8980 mL
20 mM 0.1169 mL 0.5847 mL 1.1694 mL 2.9235 mL
25 mM 0.0936 mL 0.4678 mL 0.9355 mL 2.3388 mL
30 mM 0.0780 mL 0.3898 mL 0.7796 mL 1.9490 mL
40 mM 0.0585 mL 0.2923 mL 0.5847 mL 1.4617 mL
50 mM 0.0468 mL 0.2339 mL 0.4678 mL 1.1694 mL
60 mM 0.0390 mL 0.1949 mL 0.3898 mL 0.9745 mL
80 mM 0.0292 mL 0.1462 mL 0.2923 mL 0.7309 mL
100 mM 0.0234 mL 0.1169 mL 0.2339 mL 0.5847 mL
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Prostaglandin F2α serinol amide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Prostaglandin F2α serinol amide
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HY-114810
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