Propeptin

Cat. No.: HY-N15055: Data Sheet Handling Instructions
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Propeptin is a peptide antibiotic composed of 19 amino acids. Propeptin has weaker activity against Pseudomonas aeruginosa, Mycobacterium monobacterium, and Xanthomonas oryzae. Propeptin has no effect on KB and L1210 cells of tumor cell lines, but has an inhibitory effect on prolyl endopeptidase.

For research use only. We do not sell to patients.

Propeptin Chemical Structure

CAS No. : 146764-30-9

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Description	Propeptin is a peptide antibiotic composed of 19 amino acids. Propeptin has weaker activity against Pseudomonas aeruginosa, Mycobacterium monobacterium, and Xanthomonas oryzae. Propeptin has no effect on KB and L1210 cells of tumor cell lines, but has an inhibitory effect on prolyl endopeptidase^[1].
Molecular Weight	2296.49
Formula	C₁₁₃H₁₄₂N₂₆O₂₇
CAS No.	146764-30-9
SMILES	O=C([C@@]1([H])N(CCC1)C([C@@H](NC(CNC(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC2=O)CC3=CNC4=CC=CC=C34)=O)CC(O)=O)=O)CC5=CC=C(C=C5)O)=O)CCCNC(N)=N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N6[C@@H](CCC6)C(O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)CC8=CN=CN8)=O)=O)=O)CC9=CC=CC=C9)=O)=O)=O)=O)CC%10=CC=C(C=C%10)O)=O)N[C@H]2CC%11=CNC%12=CC=CC=C%11%12
Structure Classification	Others
Initial Source	Microorganisms Microbispora sp. SNA 115
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Ken-ichi Kimura, et al. Novel propeptin analog, propeptin-2, missing two amino acid residues from the propeptin C-terminus loses antibiotic potency. J Antibiot (Tokyo). 2007 Aug;60(8):519-23. [Content Brief]

Propeptin Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propeptin146764-30-9BacterialAntibioticInhibitorinhibitorinhibit

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Propeptin

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