Phenanthrene-d₁₀

Name: Phenanthrene-d 10
Brand: MedChemExpress
SKU: HY-B1727S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1727S: Data Sheet
SDS

COA
Handling Instructions
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Phenanthrene-d₁₀ is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices. Phenanthrene induces oxidative stress and inflammation.

For research use only. We do not sell to patients.

Phenanthrene-d<sub>10</sub> Chemical Structure

Phenanthrene-d₁₀ Chemical Structure

CAS No. : 1517-22-2

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Phenanthrene-d₁₀:

Phenanthrene In-stock
Phenanthrene-¹³C₆ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Phenanthrene-d₁₀ is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices^[1]. Phenanthrene induces oxidative stress and inflammation^[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

188.30

Formula

C₁₄D₁₀

CAS No.

1517-22-2

Unlabeled CAS

85-01-8

Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=C([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2C3=C([2H])C([2H])=C([2H])C([2H])=C13

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (531.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3107 mL	26.5534 mL	53.1067 mL
5 mM	1.0621 mL	5.3107 mL	10.6213 mL
10 mM	0.5311 mL	2.6553 mL	5.3107 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Select Batch:

Data Sheet (277 KB) SDS (597 KB)

COA (256 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Sun K, et al. Subcellular distribution and biotransformation of phenanthrene in pakchoi after inoculation with endophytic Pseudomonas sp. as probed using HRMS coupled with isotope-labeling. Environ Pollut. 2018 Jun;237:858-867.;Dupuy J, et al. Effect and localization of phenanthrene in maize roots. Chemosphere. 2016 Apr;149:130-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.3107 mL	26.5534 mL	53.1067 mL	132.7669 mL
	5 mM	1.0621 mL	5.3107 mL	10.6213 mL	26.5534 mL
	10 mM	0.5311 mL	2.6553 mL	5.3107 mL	13.2767 mL
	15 mM	0.3540 mL	1.7702 mL	3.5404 mL	8.8511 mL
	20 mM	0.2655 mL	1.3277 mL	2.6553 mL	6.6383 mL
	25 mM	0.2124 mL	1.0621 mL	2.1243 mL	5.3107 mL
	30 mM	0.1770 mL	0.8851 mL	1.7702 mL	4.4256 mL
	40 mM	0.1328 mL	0.6638 mL	1.3277 mL	3.3192 mL
	50 mM	0.1062 mL	0.5311 mL	1.0621 mL	2.6553 mL
	60 mM	0.0885 mL	0.4426 mL	0.8851 mL	2.2128 mL
	80 mM	0.0664 mL	0.3319 mL	0.6638 mL	1.6596 mL
	100 mM	0.0531 mL	0.2655 mL	0.5311 mL	1.3277 mL