Perindopril arginine

Cat. No.: HY-169221 Purity: 99.32%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection.

For research use only. We do not sell to patients.

Perindopril arginine Chemical Structure

CAS No. : 612548-45-5

Size	Price	Stock
1 g		Ask For Quote & Lead Time
5 g		Ask For Quote & Lead Time

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

542.67

Formula

C₂₅H₄₆N₆O₇

CAS No.

612548-45-5

Appearance

Solid

Color

White to off-white

SMILES

N=C(N)NCCC[C@H](N)C(O)=O.CCOC([C@H](CCC)N[C@@H](C)C(N1[C@]2([H])[C@](CCCC2)([H])C[C@H]1C(O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (184.27 mM)

DMSO : 6.48 mg/mL (11.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8427 mL	9.2137 mL	18.4274 mL
5 mM	0.3685 mL	1.8427 mL	3.6855 mL
10 mM	0.1843 mL	0.9214 mL	1.8427 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.32%

Select Batch:

Data Sheet (278 KB) SDS (251 KB)

COA (261 KB) HNMR (305 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Use of Perindopril Arginine/Indapamide/Amlodipine in the Management of Hypertension in Two Sub-Saharan African Island Countries of Madagascar and Mauritius [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	1.8427 mL	9.2137 mL	18.4274 mL	46.0685 mL
	5 mM	0.3685 mL	1.8427 mL	3.6855 mL	9.2137 mL
	10 mM	0.1843 mL	0.9214 mL	1.8427 mL	4.6069 mL
H₂O	15 mM	0.1228 mL	0.6142 mL	1.2285 mL	3.0712 mL
	20 mM	0.0921 mL	0.4607 mL	0.9214 mL	2.3034 mL
	25 mM	0.0737 mL	0.3685 mL	0.7371 mL	1.8427 mL
	30 mM	0.0614 mL	0.3071 mL	0.6142 mL	1.5356 mL
	40 mM	0.0461 mL	0.2303 mL	0.4607 mL	1.1517 mL
	50 mM	0.0369 mL	0.1843 mL	0.3685 mL	0.9214 mL
	60 mM	0.0307 mL	0.1536 mL	0.3071 mL	0.7678 mL
	80 mM	0.0230 mL	0.1152 mL	0.2303 mL	0.5759 mL
	100 mM	0.0184 mL	0.0921 mL	0.1843 mL	0.4607 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.