2. Cytoskeleton
  3. Gap Junction Protein
  4. Peptide5

Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury

For research use only. We do not sell to patients.

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Peptide5 Chemical Structure

Peptide5 Chemical Structure

CAS No. : 916977-43-0

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Based on 1 publication(s) in Google Scholar

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Peptide5 Related Antibodies

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Description

Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury[1]

In Vitro

Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peptide5 Related Antibodies
In Vivo

Peptide5 is could be used to treat traumatic spinal cord injured rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1395.58

Formula

C60H98N16O20S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

VDCFLSRPTEKT
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (71.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7165 mL 3.5827 mL 7.1655 mL
5 mM 0.1433 mL 0.7165 mL 1.4331 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7165 mL 3.5827 mL 7.1655 mL 17.9137 mL
5 mM 0.1433 mL 0.7165 mL 1.4331 mL 3.5827 mL
10 mM 0.0717 mL 0.3583 mL 0.7165 mL 1.7914 mL
15 mM 0.0478 mL 0.2388 mL 0.4777 mL 1.1942 mL
20 mM 0.0358 mL 0.1791 mL 0.3583 mL 0.8957 mL
25 mM 0.0287 mL 0.1433 mL 0.2866 mL 0.7165 mL
30 mM 0.0239 mL 0.1194 mL 0.2388 mL 0.5971 mL
40 mM 0.0179 mL 0.0896 mL 0.1791 mL 0.4478 mL
50 mM 0.0143 mL 0.0717 mL 0.1433 mL 0.3583 mL
60 mM 0.0119 mL 0.0597 mL 0.1194 mL 0.2986 mL
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Peptide5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peptide5916977-43-0Peptide 5Peptide-5Gap Junction ProteinInhibitorinhibitorinhibit

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