2. Cell Cycle/DNA Damage
  3. CDK
  4. Palbociclib hydrochloride (Standard)

Palbociclib hydrochloride (Standard) 

Cat. No.: HY-50767CR Purity: ≥98%
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Palbociclib (hydrochloride) (Standard) is the analytical standard of Palbociclib (hydrochloride). This product is intended for research and analytical applications. Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

For research use only. We do not sell to patients.

Palbociclib hydrochloride (Standard) Chemical Structure

Palbociclib hydrochloride (Standard) Chemical Structure

CAS No. : 571189-11-2

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Description

Palbociclib (hydrochloride) (Standard) is the analytical standard of Palbociclib (hydrochloride). This product is intended for research and analytical applications. Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Molecular Weight

514.99

Formula

C24H30ClN7O2
CAS No.
SMILES

O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C.Cl.[37/20]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Palbociclib hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palbociclib hydrochloride (Standard)571189-11-2CDKCyclin dependent kinaseBreast cancerhepatocellular carcinomaHCCestrogen receptorERHER2cell cycleInhibitorinhibitorinhibit

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