2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. ORG 31433

ORG 31433 is an orally active peptide related to the ACTH-(4-9) analog ORG 2766 (HY-P2113). ORG 31433 shows neuroprotective effect.

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ORG 31433

ORG 31433 Chemical Structure

CAS No. : 132031-83-5

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ORG 31433 Related Antibodies

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Description

ORG 31433 is an orally active peptide related to the ACTH-(4-9) analog ORG 2766 (HY-P2113). ORG 31433 shows neuroprotective effect[1].

In Vivo

ORG 31433 (5.0 ng/kg, s.c.) facilitates passive avoidance behavior in rats[1].
ORG 31433 (10 μg/kg, p.o.) accelerates functional recovery from 6-hydroxydopamine (6-OHDA) (HY-B1081A)-induced lesions in the nucleus accumbens in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1010.25

Formula

C50H75N9O11S
CAS No.
SMILES

CCCCCCCCCCOC([C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](N)CCS(C)(=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ORG 31433 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ORG 31433132031-83-5ORG31433ORG-31433Melanocortin ReceptorMC ReceptorACTHORG 2766neuroprotective effectInhibitorinhibitorinhibit

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