2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. ONO-TR-772

ONO-TR-772 (VU6018042) is a selective TREK inhibitor (IC50: 15 nM). ONO-TR-772 enhances recognition memory in the MK-801-stimulated NOR mouse model. ONO-TR-772 can be used in the study of diseases related to cognitive impairment.

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ONO-TR-772 Chemical Structure

ONO-TR-772 Chemical Structure

CAS No. : 2640847-32-9

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ONO-TR-772 Related Antibodies

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Description

ONO-TR-772 (VU6018042) is a selective TREK inhibitor (IC50: 15 nM). ONO-TR-772 enhances recognition memory in the MK-801-stimulated NOR mouse model. ONO-TR-772 can be used in the study of diseases related to cognitive impairment[1].

Molecular Weight

479.93

Formula

C26H23ClFN3O3
CAS No.
SMILES

CC1=CC(C#CC2=CC=C(F)C=C2)=CN=C1NC(C3=C(Cl)C=CC(NC(OC(C)(C)C)=O)=C3)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ONO-TR-772 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ONO-TR-7722640847-32-9VU6018042VU 6018042VU-6018042Potassium ChannelKcsAcognitive impairmentMK-801-stimulated NOR mouse modelInhibitorinhibitorinhibit

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