2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Olmutinib hydrochloride

Olmutinib hydrochloride  (Synonyms: HM61713 hydrochloride; BI 1482694 hydrochloride)

Cat. No.: HY-19730A
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Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC.

For research use only. We do not sell to patients.

Olmutinib hydrochloride

Olmutinib hydrochloride Chemical Structure

CAS No. : 1842366-97-5

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Olmutinib hydrochloride Related Antibodies

Top Publications Citing Use of Products

    Olmutinib hydrochloride purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2018 Jul;8(4):563-574.  [Abstract]

    The protein levels of ABCG2 in MDR cells after different concentrations Olmutinib stimulation for 48 h are measured by Western blot analysis (GAPDH as loading control).

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    Description

    Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC[1][2].

    Clinical Trial
    Molecular Weight

    559.51

    Formula

    C26H28Cl2N6O2S
    CAS No.
    SMILES

    O=C(NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C=C3)=NC5=C2SC=C5)=CC=C1)C=C.Cl.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Olmutinib hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Olmutinib1842366-97-5HM61713BI 1482694HM 61713HM-61713BI1482694BI-1482694EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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