2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  3. Reactive Oxygen Species (ROS) Apoptosis
  4. NSC3852

NSC3852 exhibits anti-proliferative activity against cancer cell MCF-7. NSC3852 promotes the ROS generation, DNA damage, and apoptosis in MCF-7. NSC3852 exhibits anti-tumor against leukemia in mouse model

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NSC3852

NSC3852 Chemical Structure

CAS No. : 3565-26-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g In-stock
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50 g   Get quote  

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NSC3852 Related Antibodies

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Description

NSC3852 exhibits anti-proliferative activity against cancer cell MCF-7. NSC3852 promotes the ROS generation, DNA damage, and apoptosis in MCF-7. NSC3852 exhibits anti-tumor against leukemia in mouse model[1]

Molecular Weight

174.16

Formula

C9H6N2O2
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

OC1=C2N=CC=CC2=C(N=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 35 mg/mL (200.96 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7418 mL 28.7092 mL 57.4185 mL
5 mM 1.1484 mL 5.7418 mL 11.4837 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7418 mL 28.7092 mL 57.4185 mL 143.5462 mL
5 mM 1.1484 mL 5.7418 mL 11.4837 mL 28.7092 mL
10 mM 0.5742 mL 2.8709 mL 5.7418 mL 14.3546 mL
15 mM 0.3828 mL 1.9139 mL 3.8279 mL 9.5697 mL
20 mM 0.2871 mL 1.4355 mL 2.8709 mL 7.1773 mL
25 mM 0.2297 mL 1.1484 mL 2.2967 mL 5.7418 mL
30 mM 0.1914 mL 0.9570 mL 1.9139 mL 4.7849 mL
40 mM 0.1435 mL 0.7177 mL 1.4355 mL 3.5887 mL
50 mM 0.1148 mL 0.5742 mL 1.1484 mL 2.8709 mL
60 mM 0.0957 mL 0.4785 mL 0.9570 mL 2.3924 mL
80 mM 0.0718 mL 0.3589 mL 0.7177 mL 1.7943 mL
100 mM 0.0574 mL 0.2871 mL 0.5742 mL 1.4355 mL
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NSC3852 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC38523565-26-2NSC 3852NSC-3852Reactive Oxygen Species (ROS)ApoptosisL1210MCF-7P388Inhibitorinhibitorinhibit

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