2. Others Anti-infection Apoptosis Stem Cell/Wnt JAK/STAT Signaling Cell Cycle/DNA Damage MAPK/ERK Pathway Protein Tyrosine Kinase/RTK NF-κB
  3. Reference Standards Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB
  4. Nitidine chloride (Standard)

Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.

For research use only. We do not sell to patients.

Nitidine chloride (Standard)

Nitidine chloride (Standard) Chemical Structure

CAS No. : 13063-04-2

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Information

Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

383.82

Formula

C21H18ClNO4
CAS No.
SMILES

C[N+]1=CC2=CC(OC)=C(OC)C=C2C(C=CC3=C4)=C1C3=CC5=C4OCO5.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Nitidine chloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nitidine chloride (Standard)13063-04-2Reference StandardsParasiteApoptosisSTATTopoisomeraseERKFAKp38 MAPKNF-κBExtracellular signal regulated kinasesPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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