1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Nicotinic acid mononucleotide

Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase.

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Nicotinic acid mononucleotide Chemical Structure

Nicotinic acid mononucleotide Chemical Structure

CAS No. : 321-02-8

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Other Forms of Nicotinic acid mononucleotide:

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Description

Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase[1][2].

Molecular Weight

335.20

Formula

C11H14NO9P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H]([N+]2=CC=CC(C([O-])=O)=C2)O[C@H](COP(O)(O)=O)[C@H]1O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (29.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9833 mL 14.9165 mL 29.8329 mL
5 mM 0.5967 mL 2.9833 mL 5.9666 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.9833 mL 14.9165 mL 29.8329 mL 74.5823 mL
5 mM 0.5967 mL 2.9833 mL 5.9666 mL 14.9165 mL
10 mM 0.2983 mL 1.4916 mL 2.9833 mL 7.4582 mL
15 mM 0.1989 mL 0.9944 mL 1.9889 mL 4.9722 mL
20 mM 0.1492 mL 0.7458 mL 1.4916 mL 3.7291 mL
25 mM 0.1193 mL 0.5967 mL 1.1933 mL 2.9833 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Nicotinic acid mononucleotide
Cat. No.:
HY-128700
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