2. Apoptosis
  3. c-Myc
  4. MY05

MY05 selectively targets c-MYC in cells and disrupts MYC-MAX interaction. MY05 engages intracellular c-MYC, modulates c-MYC thermal stability, reduces c-MYC transcriptional targets, and possesses anticancer activity (TNBC, Triple-Negative Breast Cancer).

For research use only. We do not sell to patients.

MY05 Chemical Structure

MY05 Chemical Structure

CAS No. : 667909-97-9

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MY05 Related Antibodies

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Description

MY05 selectively targets c-MYC in cells and disrupts MYC-MAX interaction. MY05 engages intracellular c-MYC, modulates c-MYC thermal stability, reduces c-MYC transcriptional targets, and possesses anticancer activity (TNBC, Triple-Negative Breast Cancer)[1].
In Vitro

MY05 exhibits IC50 values of 10.6 μM, 13.5 μM and 39.4 μM in MDA-MB 231, MDA-MB 468 and MCF-7 cells, respectively[1].
MY05 promotes apoptosis and inhibits MYC-Driven mammosphere growth[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MY05 Related Antibodies
In Vivo

MY05 (10 mg/kg) inhibits MYC-driven solid tumor growth in TNBC mouse model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

346.77

Formula

C19H11ClN4O
CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

N#CC1=CC2=C(NC1=O)N(C3=CC=CC=C3)N=C2C4=CC=C(Cl)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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MY05 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MY05667909-97-9MY 05MY-05c-MycMycTNBCTriple-Negative Breast Cancerc-MYCInhibitorinhibitorinhibit

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