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  4. Lyngbya majuscule
  5. Microcolin B

Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule.

For research use only. We do not sell to patients.

Microcolin B

Microcolin B Chemical Structure

CAS No. : 141205-32-5

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Based on 1 publication(s) in Google Scholar

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Description

Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule[1].

Molecular Weight

731.96

Formula

C39H65N5O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C([C@H]2N(C([C@H](C(C)C)N(C([C@H]([C@H](OC(C)=O)C)NC([C@H](CC(C)C)N(C([C@H](C)C[C@H](C)CCCC)=O)C)=O)=O)C)=O)CCC2)=O)[C@@H](C)C=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (136.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3662 mL 6.8310 mL 13.6619 mL
5 mM 0.2732 mL 1.3662 mL 2.7324 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3662 mL 6.8310 mL 13.6619 mL 34.1549 mL
5 mM 0.2732 mL 1.3662 mL 2.7324 mL 6.8310 mL
10 mM 0.1366 mL 0.6831 mL 1.3662 mL 3.4155 mL
15 mM 0.0911 mL 0.4554 mL 0.9108 mL 2.2770 mL
20 mM 0.0683 mL 0.3415 mL 0.6831 mL 1.7077 mL
25 mM 0.0546 mL 0.2732 mL 0.5465 mL 1.3662 mL
30 mM 0.0455 mL 0.2277 mL 0.4554 mL 1.1385 mL
40 mM 0.0342 mL 0.1708 mL 0.3415 mL 0.8539 mL
50 mM 0.0273 mL 0.1366 mL 0.2732 mL 0.6831 mL
60 mM 0.0228 mL 0.1138 mL 0.2277 mL 0.5692 mL
80 mM 0.0171 mL 0.0854 mL 0.1708 mL 0.4269 mL
100 mM 0.0137 mL 0.0683 mL 0.1366 mL 0.3415 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Microcolin B
Cat. No.:
HY-130999
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