1. GPCR/G Protein Neuronal Signaling
  2. MCHR1 (GPR24)
  3. MCH(human, mouse, rat)

MCH(human, mouse, rat)  (Synonyms: Melanin-concentrating hormone(human, mouse, rat))

Cat. No.: HY-P1205
Handling Instructions

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively.

For research use only. We do not sell to patients.

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MCH(human, mouse, rat) Chemical Structure

MCH(human, mouse, rat) Chemical Structure

CAS No. : 128315-56-0

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Description

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].

IC50 & Target

Binding IC50: 0.3 nM (MCH1R)
IC50: 1.5 nM (MCH1R)[1]

Molecular Weight

2386.84

Formula

C105H160N30O26S4

CAS No.
Sequence Shortening

DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MCH(human, mouse, rat)
Cat. No.:
HY-P1205
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