2. Academic Validation
  3. Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. I. Taxonomy, production, isolation and biological properties

Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. I. Taxonomy, production, isolation and biological properties

  • J Antibiot (Tokyo). 1997 Nov;50(11):926-31. doi: 10.7164/antibiotics.50.926.
M Igarashi 1,  N Kinoshita,  T Ikeda,  E Nakagawa,  M Hamada,  T Takeuchi
Affiliations

Affiliation

  • 1 Institute of Microbial Chemistry, Tokyo, Japan.
PMID: 9592565 DOI: 10.7164/antibiotics.50.926
Abstract

Formamicin, an antifungal Antibiotic, was isolated from the cultured broth of an actinomycete strain. The strain was isolated from a soil collected at Setagaya-ku, Tokyo, Japan, and identified as Saccharothrix sp. MK27-91F2. Formamicin was extracted with acetone from cultured mycelia and purified by silicagel and Sephadex LH-20 column chromatographies and CPC (Centrifugal liquid-liquid Partition Chromatography). Formamicin showed strong antimicrobial activity against phytopathogenic fungi.

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