2. Academic Validation
  3. Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17

Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17

  • J Antibiot (Tokyo). 1998 Feb;51(2):130-5. doi: 10.7164/antibiotics.51.130.
I Momose 1,  N Kinoshita,  R Sawa,  H Naganawa,  H Iinuma,  M Hamada,  T Takeuchi
Affiliations

Affiliation

  • 1 Institute of Microbial Chemistry, Tokyo, Japan.
PMID: 9544933 DOI: 10.7164/antibiotics.51.130
Abstract

A new Antibiotic designated nothramicin was isolated from the culture broth of Nocardia sp. MJ896-43F17 which was closely related to Nocardia brasiliensis. It was isolated by the Diaion HP-20 column chromatography, butyl acetate extraction and purified by HPLC. It inhibited the growth of mycobacteria at the concentration of 1.56 approximately 25 microg/ml. Nothramicin was revealed to be a new member of anthracycline Antibiotics by the various spectroscopies.

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