2. Academic Validation
  3. A new isopatulin derivative pintulin produced by Penicillium vulpinum F-4148 taxonomy, isolation, physico-chemical properties, structure and biological properties

A new isopatulin derivative pintulin produced by Penicillium vulpinum F-4148 taxonomy, isolation, physico-chemical properties, structure and biological properties

  • J Antibiot (Tokyo). 1996 Oct;49(10):985-9. doi: 10.7164/antibiotics.49.985.
A Mikami 1,  T Okazaki,  N Sakai,  T Ichihara,  K Hanada,  K Mizoue
Affiliations

Affiliation

  • 1 Medicinal Research Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama.
PMID: 8968391 DOI: 10.7164/antibiotics.49.985
Abstract

During our screening program of natural products from Fungal metabolites for drugs effective against tumor cell lines, we discovered a new isopatulin derivative, pintulin, from the fermentation broth of Penicillium vulpinum F-4148. Pintulin shows weak activity against tumor cell lines, compared to that of adriamycin.

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Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-N15112
    Anticancer Agent