Isolation of

• Peptides. 1993 Mar-Apr;14(2):131-5. doi: 10.1016/0196-9781(93)90020-h.

K Carstensen ¹,  I D McFarlane,  K L Rinehart,  D Hudman,  F Sun,  C J Grimmelikhuijzen

Affiliations collapse

Affiliation

• 1 Center for Molecular Neurobiology (ZMNH), University of Hamburg, Germany.

PMID: 8483793 DOI: 10.1016/0196-9781(93)90020-h

Abstract

Using a radioimmunoassay against the C-terminal sequence Arg-Pro-NH2 (RPamide) we have isolated the neuropeptide <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II) from extracts of the sea anemone Anthopleura elegantissima. Addition of low concentrations of Antho-RPamide II to a tentacle preparation of sea anemones inhibited the spontaneous, rhythmic contractions, suggesting that the peptide is a neurotransmitter or neuromodulator.

Figures

Products

• Cat. No.
  Product Name
  Description
  Target
  Research Area
• HY-P2152A
  Antho-RPamide II hydrochloride
  Neuropeptide
  Others
  Neurological Disease