1. Academic Validation
  2. Antibiotics from basidiomycetes. IX. Oudemansin, an antifungal antibiotic from Oudemansiella mucida (Schrader ex Fr.) Hoehnel (Agaricales)

Antibiotics from basidiomycetes. IX. Oudemansin, an antifungal antibiotic from Oudemansiella mucida (Schrader ex Fr.) Hoehnel (Agaricales)

  • J Antibiot (Tokyo). 1979 Nov;32(11):1112-7. doi: 10.7164/antibiotics.32.1112.
T Anke H J Hecht G Schramm W Steglich
Abstract

From mycelial cultures of Oudemansiella mucida a crystalline optically active Antibiotic, oudemansin (2), has been isolated; its structure is closely related to strobilurin A (1). The relative configuration of oudemansin have been determined by X-ray analysis. The Antibiotic exhibits strong Antifungal properties and inhibits respiration in fungi, cells of the ascitic form of EHRLICH carcinoma, and rat liver mitochondria.

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