2. Academic Validation
  3. β-Caryophyllene modulates the JAK2/STAT3 signaling pathway to downregulate neutrophil extracellular traps and alleviate cerebral ischemia-reperfusion injury

β-Caryophyllene modulates the JAK2/STAT3 signaling pathway to downregulate neutrophil extracellular traps and alleviate cerebral ischemia-reperfusion injury

  • Metab Brain Dis. 2025 Oct 30;40(8):301. doi: 10.1007/s11011-025-01723-6.
Zhengze Shen 1,  Zhongliang Xu 1,  Qiusha Liu 1,  Sha Liu 1,  Shengwei Liu 2
Affiliations

Affiliations

  • 1 Department of Pharmacy, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China.
  • 2 Department of Pharmacy, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China. shengweil@163.com.
PMID: 41165931 DOI: 10.1007/s11011-025-01723-6
Keywords

Cerebral ischemia reperfusion injury; JAK2/STAT3; Neutrophil extracellular traps; Oxidative stress; Β-Caryophyllene.

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