2. Academic Validation
  3. The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

  • Front Cell Infect Microbiol. 2018 Jul 4:8:230. doi: 10.3389/fcimb.2018.00230.
Jinshui Lin 1 2,  Juanli Cheng 1 2,  Yao Wang 3 4,  Xihui Shen 3 4
Affiliations

Affiliations

  • 1 Shaanxi Engineering and Technological Research Center for Conservation and Utilization of Regional Biological Resources, Yan'an University, Yan'an, China.
  • 2 College of Life Sciences, Yan'an University, Yan'an, China.
  • 3 Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, China.
  • 4 State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
PMID: 30023354 DOI: 10.3389/fcimb.2018.00230
Abstract

The Pseudomonas Quinolone signal (PQS) has been studied primarily in the context of its role as a quorum-sensing signaling molecule. Recent data suggest, however, that this molecule may also function to mediate iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, or to exert host immune modulatory activities.

Keywords

PQS; Pseudomonas aeruginosa; cytotoxicity; immune regulation; iron acquisition; outer-membrane vesicles; quorum sensing.

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