2. Academic Validation
  3. Biphenomycin A production by a mixed culture

Biphenomycin A production by a mixed culture

  • Appl Environ Microbiol. 1992 Dec;58(12):3879-82. doi: 10.1128/aem.58.12.3879-3882.1992.
M Ezaki 1,  M Iwami,  M Yamashita,  T Komori,  K Umehara,  H Imanaka
Affiliations

Affiliation

  • 1 Exploratory Research Laboratory, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
PMID: 1476432 DOI: 10.1128/aem.58.12.3879-3882.1992
Abstract

Production of biphenomycin A by Streptomyces griseorubiginosus 43708 was stimulated by a mixed culture with a partner strain, Pseudomonas maltophilia 1928. This stimulatory effect on biphenomycin A accumulation by the mixed culture was caused by the Enzyme activity which strain 1928 possessed. It is suggested that in a mixed culture strain 43708 produces a precursor of biphenomycin A in culture broth and that strain 1928 converts the precursor to biphenomycin A.

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