2. Academic Validation
  3. Pelorol from the tropical marine sponge Dactylospongia elegans

Pelorol from the tropical marine sponge Dactylospongia elegans

  • J Nat Prod. 2000 Aug;63(8):1150-2. doi: 10.1021/np990502u.
E Goclik 1,  G M König,  A D Wright,  R Kaminsky
Affiliations

Affiliation

  • 1 Institute for Pharmaceutical Biology, Technical University Braunschweig, Mendelssohnstrasse 1, D-38106 Braunschweig, Germany.
PMID: 10978215 DOI: 10.1021/np990502u
Abstract

From the dichloromethane solubles of the tropical marine Sponge Dactylospongia elegans, a new aromatic substituted sesquiterpene, pelorol (1), and the known sesquiterpene, ilimaquinone (2), were isolated. The structures of 1 and 2 were deduced from their spectroscopic data. The biological activities of compounds 1 and 2 were assessed in a variety of bioassays, and both compounds were found to have weak antitrypanosomal and antiplasmodial effects.

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