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Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor.

For research use only. We do not sell to patients.

Matriptase-IN-2 Chemical Structure

Matriptase-IN-2 Chemical Structure

CAS No. : 1268874-09-4

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Based on 1 publication(s) in Google Scholar

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Matriptase-IN-2 Related Antibodies

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Description

Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor[1].

Molecular Weight

830.62

Formula

C33H35Cl2F6N5O7S
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

OC(C(F)(F)F)=O.ClC1=C(C2=CC(S(N[C@H](C(N3CCC(CC3)CCN)=O)CC4=CC(C(N)=N)=CC=C4)(=O)=O)=CC=C2)C=CC(Cl)=C1.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 83 mg/mL (99.93 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2039 mL 6.0196 mL 12.0392 mL
5 mM 0.2408 mL 1.2039 mL 2.4078 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.60%

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2039 mL 6.0196 mL 12.0392 mL 30.0980 mL
5 mM 0.2408 mL 1.2039 mL 2.4078 mL 6.0196 mL
10 mM 0.1204 mL 0.6020 mL 1.2039 mL 3.0098 mL
15 mM 0.0803 mL 0.4013 mL 0.8026 mL 2.0065 mL
20 mM 0.0602 mL 0.3010 mL 0.6020 mL 1.5049 mL
25 mM 0.0482 mL 0.2408 mL 0.4816 mL 1.2039 mL
30 mM 0.0401 mL 0.2007 mL 0.4013 mL 1.0033 mL
40 mM 0.0301 mL 0.1505 mL 0.3010 mL 0.7524 mL
50 mM 0.0241 mL 0.1204 mL 0.2408 mL 0.6020 mL
60 mM 0.0201 mL 0.1003 mL 0.2007 mL 0.5016 mL
80 mM 0.0150 mL 0.0752 mL 0.1505 mL 0.3762 mL
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Matriptase-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Matriptase-IN-21268874-09-4OthersInhibitorinhibitorinhibit

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