1. GPCR/G Protein Immunology/Inflammation
  2. CXCR
  3. LIH383 TFA

LIH383 TFA is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 TFA efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling.

For research use only. We do not sell to patients.

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LIH383 TFA Chemical Structure

LIH383 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

LIH383 TFA is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 TFA efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1].

Molecular Weight

997.22 (free base)

Formula

C45H72N16O8S.xC2HF3O2

Appearance

Solid

Sequence

Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2

Sequence Shortening

FGGFMRRK-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LIH383 TFA
Cat. No.:
HY-P10333A
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