2. Anti-infection
  3. HIV
  4. Lenacapavir sodium

Lenacapavir (GS-6207) sodium is a HIV-1 capsid inhibitor. Lenacapavir sodium shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir sodium displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs).

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Lenacapavir sodium

Lenacapavir sodium Chemical Structure

CAS No. : 2283356-12-5

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Lenacapavir sodium Related Antibodies

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Description

Lenacapavir (GS-6207) sodium is a HIV-1 capsid inhibitor. Lenacapavir sodium shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir sodium displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs)[1].

Clinical Trial
Molecular Weight

990.26

Formula

C39H31ClF10N7NaO5S2
CAS No.
SMILES

FC1=CC(F)=CC(C[C@@H](C2=NC(C#CC(S(=O)(C)=O)(C)C)=CC=C2C3=CC=C(Cl)C4=C3N(CC(F)(F)F)N=C4N([Na])S(=O)(C)=O)NC(CN5C(C(F)(F)[C@@]6([H])[C@]7([H])C6)=C7C(C(F)(F)F)=N5)=O)=C1
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Lenacapavir sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lenacapavir2283356-12-5GS-6207GS6207GS 6207HIVHuman immunodeficiency virusCapsidinhibitorMT-4 cellsPeripheral blood mononuclear cellInhibitorinhibit

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