L-β-Ethynylserine

Cat. No.: HY-164745 Purity: 99.98%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

L-β-ethynylserine (βES) is a threonine analog. L-β-ethynylserine is efficiently incorporated into newly synthesized proteins, and allows their selective visualization or enrichment through bioorthogonal ligation to fluorescent dyes or affinity tags, respectively.

For research use only. We do not sell to patients.

L-β-Ethynylserine Chemical Structure

CAS No. : 65207-64-9

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

129.11

Formula

C₅H₇NO₃

CAS No.

65207-64-9

Appearance

Solid

Color

Off-white to light yellow

SMILES

C#C[C@@H](O)[C@H](N)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 35 mg/mL (271.09 mM; Need ultrasonic)

DMSO : 2 mg/mL (15.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.7453 mL	38.7267 mL	77.4533 mL
5 mM	1.5491 mL	7.7453 mL	15.4907 mL
10 mM	0.7745 mL	3.8727 mL	7.7453 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.98%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (249 KB) HNMR (230 KB) RP-HPLC (238 KB) MS (72 KB)

Handling Instructions (2659 KB)

References

[1]. Ignacio BJ, Dijkstra J, Mora N, et al. THRONCAT: metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog. Nat Commun. 2023;14(1):3367. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	7.7453 mL	38.7267 mL	77.4533 mL	193.6333 mL
	5 mM	1.5491 mL	7.7453 mL	15.4907 mL	38.7267 mL
	10 mM	0.7745 mL	3.8727 mL	7.7453 mL	19.3633 mL
	15 mM	0.5164 mL	2.5818 mL	5.1636 mL	12.9089 mL
H₂O	20 mM	0.3873 mL	1.9363 mL	3.8727 mL	9.6817 mL
	25 mM	0.3098 mL	1.5491 mL	3.0981 mL	7.7453 mL
	30 mM	0.2582 mL	1.2909 mL	2.5818 mL	6.4544 mL
	40 mM	0.1936 mL	0.9682 mL	1.9363 mL	4.8408 mL
	50 mM	0.1549 mL	0.7745 mL	1.5491 mL	3.8727 mL
	60 mM	0.1291 mL	0.6454 mL	1.2909 mL	3.2272 mL
	80 mM	0.0968 mL	0.4841 mL	0.9682 mL	2.4204 mL
	100 mM	0.0775 mL	0.3873 mL	0.7745 mL	1.9363 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.