2. GPCR/G Protein MAPK/ERK Pathway Stem Cell/Wnt
  3. Ras p38 MAPK Raf MEK ERK
  4. KRAS G12D-IN-30

KRAS G12D-IN-30 (Compound 4) is a KRAS inhibitor. KRAS G12D-IN-30 inhibits the activation of the downstream MAPK signaling cascade (Raf1-MEK-ERK) by blocking the activity of the KRAS G12 mutant. KRAS G12D-IN-30 can be used for the research of cancer.

For research use only. We do not sell to patients.

KRAS G12D-IN-30

KRAS G12D-IN-30 Chemical Structure

CAS No. : 3022287-75-5

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KRAS G12D-IN-30 Related Antibodies

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Description

KRAS G12D-IN-30 (Compound 4) is a KRAS inhibitor. KRAS G12D-IN-30 inhibits the activation of the downstream MAPK signaling cascade (Raf1-MEK-ERK) by blocking the activity of the KRAS G12 mutant. KRAS G12D-IN-30 can be used for the research of cancer[1].

IC50 & Target[1]

KRas G12D

 

Molecular Weight

587.74

Formula

C30H37N9O2S
CAS No.
SMILES

N#CC1=C(N2CC3(C2)CCC(S4)=C3C(C#N)=C4N)N=C(OCC5(CC5)CN6CCOCC6)N=C1N7C[C@H]8N[C@H](CC8)C7
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS G12D-IN-30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12D-IN-303022287-75-5Rasp38 MAPKRafMEKERKRaf kinasesMitogen-activated protein kinase kinaseMAPKKMAP2KExtracellular signal regulated kinasesKRASKRAS G12 mutantRaf1-MEK-ERKMAPKcancerInhibitorinhibitorinhibit

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