1. Autophagy Neuronal Signaling
  2. PINK1/Parkin
  3. Kinetin triphosphate tetrasodium

Kinetin triphosphate tetrasodium  (Synonyms: 6-Fu-ATP tetrasodium; KTP tetrasodium)

Cat. No.: HY-134398A Purity: 99.92%
Handling Instructions Technical Support

Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research.

For research use only. We do not sell to patients.

Kinetin triphosphate tetrasodium

Kinetin triphosphate tetrasodium Chemical Structure

Size Price Stock Quantity
Solvent
5 mg (100 mM * 74.1 μL in Water) In-stock
Solvent
10 mg (100 mM * 148.1 μL in Water) In-stock

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Based on 1 publication(s) in Google Scholar

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Description

Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research[1].

In Vitro

Kinetin triphosphate tetrasodium can act as a phosphate donor for PINK1 to recognize the T257 autophosphorylation site, and can restore the catalytic activity of PINK1 G309D to close to WT levels in HeLa cells in vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

675.19

Formula

C15H16N5Na4O14P3

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=P(O[Na])(O[Na])OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O[Na])=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Kinetin triphosphate tetrasodium
Cat. No.:
HY-134398A
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