2. Isotope-Labeled Compounds
  3. Internal Standard for Clinical Mass Spectrometry
  4. Vitamins

Vitamins

Vitamins are one of the six essential nutrients needed by the human body (vitamins, proteins, fats, minerals, water and carbohydrates) for normal functioning. These are micronutrients that play an important role in the growth, metabolism, and development of the human body. Most vitamins cannot be synthesized in the body or not in sufficient quantities and must be obtained through diet and other means. Although the daily requirement of the human body for vitamins is very small, once deficient, it can cause a range of symptoms associated with "vitamin deficiency". Vitamin deficiency can cause a number of diseases such as rickets (vitamin D deficiency), scurvy (vitamin C deficiency), angular cheilitis (vitamin B deficiency), and xerophthalmia (vitamin A deficiency). Different vitamins play a variety of roles in the body. It is difficult to monitor human body vitamin levels or identify a potential vitamin deficiency. The isotope labeled vitamins play an important role in the detection of vitamin content in the human body. Isotope-labeled compounds are used as internal standards to make the quantification more accurate and sensitive in clinical mass spectrometry.

Vitamins (109):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0150S
    Nicotinamide-d4 347841-88-7 99.71%
    Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
    Nicotinamide-d<sub>4</sub>
  • HY-15331
    VD3-d6 118584-54-6 99.45%
    VD3-d6 (Vitamin D3-26,26,26,27,27,27-d6) is deuterated VD3. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    VD3-d<sub>6</sub>
  • HY-76814
    Calcitriol-d6 78782-99-7 99.06%
    Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR).
    Calcitriol-d<sub>6</sub>
  • HY-B0143S2
    Niacin-d4 66148-15-0 99.15%
    Niacin-d4 is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
    Niacin-d<sub>4</sub>
  • HY-13332
    Calcifediol-d6 78782-98-6 98.91%
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand.
    Calcifediol-d<sub>6</sub>
  • HY-A0020S
    Eldecalcitol-d6 99.23%
    Eldecalcitol-d6 is the deuterium labeled Eldecalcitol. Eldecalcitol is an orally active analogue of active vitamin D used in the treatment of osteoporosis.
    Eldecalcitol-d<sub>6</sub>
  • HY-15330
    Vitamin D2-d3 1217448-46-8 98.60%
    Vitamin D2-d3 (Ergocalciferol-d3) is the deuterium labeled vitamin D2.
    Vitamin D2-d<sub>3</sub>
  • HY-N7148S
    α-Vitamin E-d6 113892-08-3 ≥99.0%
    α-Vitamin E-d6 is the deuterium labeled α-Vitamin E.
    α-Vitamin E-d<sub>6</sub>
  • HY-15329
    Maxacalcitol-d6 99.63%
    Maxacalcitol-d66 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
    Maxacalcitol-d<sub>6</sub>
  • HY-B0511S
    Biotin-d2-1 1217481-41-8 99.65%
    Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    Biotin-d<sub>2</sub>-1
  • HY-B0143S3
    Niacin-13C6 1189954-79-7 99.90%
    Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
    Niacin-<sup>13</sup>C<sub>6</sub>
  • HY-B0166S
    L-Ascorbic acid-13C6 1354064-87-1 99.90%
    L-Ascorbic acid-13C6 is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
    L-Ascorbic acid-<sup>13</sup>C<sub>6</sub>
  • HY-144243S
    Vitamin B5-d4 calcium 99.51%
    Vitamin B5-d4 (calcium) is the deuterium labeled Vitamin B5 calcium.
    Vitamin B5-d<sub>4</sub> calcium
  • HY-N0411S1
    β-Carotene-d8 53163-44-3
    β-Carotene-d8 is the deuterium labeled β-Carotene (HY-N0411).
    β-Carotene-d<sub>8</sub>
  • HY-32351S
    Calcifediol-d3 140710-94-7 99.06%
    Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.
    Calcifediol-d<sub>3</sub>
  • HY-B0166S1
    L-Ascorbic acid-13C 178101-88-7 99.90%
    L-Ascorbic acid-13C is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
    L-Ascorbic acid-<sup>13</sup>C
  • HY-15332
    Alfacalcidol-d6 1641940-94-4 ≥98.0%
    Alfacalcidol-d6 is the deuterium labeled Alfacalcidol. Alfacalcidol is a non-selective VDR activator.
    Alfacalcidol-d<sub>6</sub>
  • HY-14649S4
    Retinoic acid-d5 78996-15-3 98.25%
    Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid-d<sub>5</sub>
  • HY-N0684S
    Vitamin K1-d7 1373049-34-3 ≥98.0%
    Vitamin K1-d7 is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1-d<sub>7</sub>
  • HY-N0157S1
    Orotic acid-13C,15N2 monohydrate 1346602-15-0 99.93%
    Orotic acid-13C,15N2 (monohydrate) is the 13C and 15N labeled Orotic acid. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.
    Orotic acid-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> monohydrate