2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. Isomartynoside

Isomartynoside is a potent angiotensin converting enzyme (ACE) inhibitor with an IC50 value of 505.9 µM. Isomartynoside is a phenylpropanoid glycoside that can be found in Galeopsis pubescens. IC50: 505.9 µM (ACE)

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Isomartynoside

Isomartynoside Chemical Structure

CAS No. : 94410-22-7

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Based on 1 publication(s) in Google Scholar

Isomartynoside Related Antibodies

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Description

Isomartynoside is a potent angiotensin converting enzyme (ACE) inhibitor with an IC50 value of 505.9 µM. Isomartynoside is a phenylpropanoid glycoside that can be found in Galeopsis pubescens[1][2]. IC50: 505.9 µM (ACE)[1]

IC50 & Target

IC50: 505.9 µM (ACE)[1]
Molecular Weight

652.64

Formula

C31H40O15
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]([C@@H](O)[C@H](C)O1)O)[C@]1([H])O[C@@H]2[C@H]([C@@H](O[C@H](COC(/C=C/C3=CC(OC)=C(O)C=C3)=O)[C@H]2O)OCCC4=CC(O)=C(OC)C=C4)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (153.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5322 mL 7.6612 mL 15.3224 mL
5 mM 0.3064 mL 1.5322 mL 3.0645 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5322 mL 7.6612 mL 15.3224 mL 38.3060 mL
5 mM 0.3064 mL 1.5322 mL 3.0645 mL 7.6612 mL
10 mM 0.1532 mL 0.7661 mL 1.5322 mL 3.8306 mL
15 mM 0.1021 mL 0.5107 mL 1.0215 mL 2.5537 mL
20 mM 0.0766 mL 0.3831 mL 0.7661 mL 1.9153 mL
25 mM 0.0613 mL 0.3064 mL 0.6129 mL 1.5322 mL
30 mM 0.0511 mL 0.2554 mL 0.5107 mL 1.2769 mL
40 mM 0.0383 mL 0.1915 mL 0.3831 mL 0.9576 mL
50 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7661 mL
60 mM 0.0255 mL 0.1277 mL 0.2554 mL 0.6384 mL
80 mM 0.0192 mL 0.0958 mL 0.1915 mL 0.4788 mL
100 mM 0.0153 mL 0.0766 mL 0.1532 mL 0.3831 mL
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Isomartynoside Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isomartynoside94410-22-7Angiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

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