2. Anti-infection
  3. Parasite
  4. Insecticidal agent 24

Insecticidal agent 24 is an orally active pyridylspiroindoline frontrunner. Insecticidal agent 24 has antiplasmodial activity (Pf NF54 IC50: 0.08 μM). Insecticidal agent 24 inhibits hERG activity (IC50: 6.5 μM). Insecticidal agent 24 reduces parasitemia in a humanized immunodeficient NSG mouse Plasmodium falciparum infection model.

For research use only. We do not sell to patients.

Insecticidal agent 24 Chemical Structure

Insecticidal agent 24 Chemical Structure

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Insecticidal agent 24 Related Antibodies

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Description

Insecticidal agent 24 is an orally active pyridylspiroindoline frontrunner. Insecticidal agent 24 has antiplasmodial activity (Pf NF54 IC50: 0.08 μM). Insecticidal agent 24 inhibits hERG activity (IC50: 6.5 μM). Insecticidal agent 24 reduces parasitemia in a humanized immunodeficient NSG mouse Plasmodium falciparum infection model[1].

Molecular Weight

415.53

Formula

C26H29N3O2
SMILES

COC1=CC2=C(N(C3=CC=NC=C3)CC24CCN(CC4)C)C=C1OCC5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Insecticidal agent 24 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Insecticidal agent 24Insecticidal agent24Insecticidal agent-24ParasiteAntiplasmodialpyridylspiroindoline frontrunnerP. falciparumK17G8Dd2Inhibitorinhibitorinhibit

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