2. Neuronal Signaling
  3. Transthyretin (TTR)
  4. Inotersen

Inotersen  (Synonyms: GSK-2998728; ISIS-420915)

Cat. No.: HY-112974 Purity: 96.44%
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Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR).

For research use only. We do not sell to patients.

DNA, d(P-thio)([2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-G-T-T-A-m5C-A-T-G-A-A-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC)

Inotersen Chemical Structure

CAS No. : 1492984-65-2

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Based on 1 publication(s) in Google Scholar

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Inotersen Related Antibodies

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Description

Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR).

Clinical Trial
Molecular Weight

7183.08

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Inotersen]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Purity & Documentation
References
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Inotersen Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Inotersen1492984-65-2GSK-2998728 ISIS-420915GSK2998728GSK 2998728ISIS420915ISIS 420915ISIS-420915Transthyretin (TTR)thyroxine-binding prealbuminInhibitorinhibitorinhibit

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