1. Neuronal Signaling
  2. Amyloid-β
  3. Ile-Phe

Ile-Phe is a dipeptide that self-associates in aqueous solution to form a transparent thermoreversible gel formed by a network of fibrillar nanostructures. It may be involved in triggering self-assembly processes such as amyloid formation.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ile-Phe Chemical Structure

Ile-Phe Chemical Structure

CAS No. : 22951-98-0

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Description

Ile-Phe is a dipeptide that self-associates in aqueous solution to form a transparent thermoreversible gel formed by a network of fibrillar nanostructures. It may be involved in triggering self-assembly processes such as amyloid formation.

Molecular Weight

278.35

Formula

C15H22N2O3

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ile-Phe

Sequence Shortening

IF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 11.11 mg/mL (39.91 mM; ultrasonic and adjust pH to 2 with 1 M HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5926 mL 17.9630 mL 35.9260 mL
5 mM 0.7185 mL 3.5926 mL 7.1852 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5926 mL 17.9630 mL 35.9260 mL 89.8150 mL
5 mM 0.7185 mL 3.5926 mL 7.1852 mL 17.9630 mL
10 mM 0.3593 mL 1.7963 mL 3.5926 mL 8.9815 mL
15 mM 0.2395 mL 1.1975 mL 2.3951 mL 5.9877 mL
20 mM 0.1796 mL 0.8981 mL 1.7963 mL 4.4907 mL
25 mM 0.1437 mL 0.7185 mL 1.4370 mL 3.5926 mL
30 mM 0.1198 mL 0.5988 mL 1.1975 mL 2.9938 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ile-Phe
Cat. No.:
HY-P4637
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