Hydroxyectoin (Synonyms: Pyrostatin A; 5-Hydroxyectoine)

Cat. No.: HY-108032 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Hydroxyectoin (Pyrostatin A) is a competitive inhibitor of GlcNAcase, with the K_i of 1.7 μM.

For research use only. We do not sell to patients.

Hydroxyectoin Chemical Structure

CAS No. : 165542-15-4

Size	Price	Stock
50 mg		Ask For Quote & Lead Time

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Description

Hydroxyectoin (Pyrostatin A) is a competitive inhibitor of GlcNAcase, with the K_i of 1.7 μM^[1].

Molecular Weight

158.16

Formula

C₆H₁₀N₂O₃

CAS No.

165542-15-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

OC([C@@H]1[C@H](CN=C(C)N1)O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Streptomyces sp

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (316.14 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.3227 mL	31.6136 mL	63.2271 mL
5 mM	1.2645 mL	6.3227 mL	12.6454 mL
10 mM	0.6323 mL	3.1614 mL	6.3227 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.0%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (251 KB) HNMR (236 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Daniel Appel, et al. The pyrostatins A and B do not inhibit N-acetyl-ß-Dglucosaminidase. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1106-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.3227 mL	31.6136 mL	63.2271 mL	158.0678 mL
	5 mM	1.2645 mL	6.3227 mL	12.6454 mL	31.6136 mL
	10 mM	0.6323 mL	3.1614 mL	6.3227 mL	15.8068 mL
	15 mM	0.4215 mL	2.1076 mL	4.2151 mL	10.5379 mL
	20 mM	0.3161 mL	1.5807 mL	3.1614 mL	7.9034 mL
	25 mM	0.2529 mL	1.2645 mL	2.5291 mL	6.3227 mL
	30 mM	0.2108 mL	1.0538 mL	2.1076 mL	5.2689 mL
	40 mM	0.1581 mL	0.7903 mL	1.5807 mL	3.9517 mL
	50 mM	0.1265 mL	0.6323 mL	1.2645 mL	3.1614 mL
	60 mM	0.1054 mL	0.5269 mL	1.0538 mL	2.6345 mL
	80 mM	0.0790 mL	0.3952 mL	0.7903 mL	1.9758 mL
	100 mM	0.0632 mL	0.3161 mL	0.6323 mL	1.5807 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Hydroxyectoin Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxyectoin165542-15-4Pyrostatin A 5-HydroxyectoineOGAO-GlcNAc hydrolaseO-GlcNAcaseStreptomyces sp.Inhibitorinhibitorinhibit

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Hydroxyectoin (Synonyms: Pyrostatin A; 5-Hydroxyectoine)

Hydroxyectoin Related Antibodies

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